CAN-11-0907R1 CXCR3 enhances a T cell dependent epidermal proliferative response and promotes skin tumorigenesis
نویسندگان
چکیده
Department of Otolaryngology and John Cochran VA Medical Center, Department of Pathology and Immunology, Center For Immunology, Washington University School of Medicine, 660 South Euclid Avenue, St. Louis, Missouri, 63110, USA. *AEW and JJB contributed equally to this work Running Title: CXCR3 in skin tumorigenesis
منابع مشابه
CXCR3 enhances a T-cell-dependent epidermal proliferative response and promotes skin tumorigenesis.
The chemokine receptor CXCR3 has been proposed to play a critical role in host antitumor responses. In this study, we defined CXCR3-expressing immune cell infiltration in human skin squamous cell carcinomas and then used CXCR3-deficient mice to assess the contribution of CXCR3 to skin tumorigenesis. Our studies employed two established protocols for chemical skin carcinogenesis [methylcholanthr...
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